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The Tangled History of MRNA Vaccines

The Tangled History of MRNA Vaccines

Hundreds of scientists had worked on mRNA vaccines for decades before the coronavirus pandemic brought a breakthrough.

Women Less Likely to Win Major Research Awards

Women Less Likely to Win Major Research Awards

Although the gap is narrowing, prestigious prizes are still more likely to go to men, finds an analysis of gender bias in the world's top science awards.

Preprint Advocates Must Also Fight for Research Integrity

Preprint Advocates Must Also Fight for Research Integrity

Efforts to share research with the public must include mechanisms to prevent harm resulting from low-quality work.

Replication Studies for Undergraduate Theses to Improve Science and Education | FULL TEXT

Replication Studies for Undergraduate Theses to Improve Science and Education | FULL TEXT

FULL TEXT.  Requiring undergraduate students to perform what is termed original research for their thesis, an investigation that cannot constitute a replication of an existing study, is a failed opportunity for science and education, argues Daniel Quintana.

Replication Studies for Undergraduate Theses to Improve Science and Education

Replication Studies for Undergraduate Theses to Improve Science and Education

Requiring undergraduate students to perform what is termed original research for their thesis, an investigation that cannot constitute a replication of an existing study, is a failed opportunity for science and education.

Automated Detection of Poor-quality Data: Case Studies in Healthcare

Automated Detection of Poor-quality Data: Case Studies in Healthcare

The detection and removal of poor-quality data in a training set is crucial to achieve high-performing AI models. In healthcare, data can be inherently poor-quality due to uncertainty or subjectivity, but as is often the case, the requirement for data privacy restricts AI practitioners from accessing raw training data, meaning manual visual verification of private patient data is not possible. Here we describe a novel method for automated identification of poor-quality data, called Untrainable Data Cleansing. This method is shown to have numerous benefits including protection of private patient data; improvement in AI generalizability; reduction in time, cost, and data needed for training; all while offering a truer reporting of AI performance itself. Additionally, results show that Untrainable Data Cleansing could be useful as a triage tool to identify difficult clinical cases that may warrant in-depth evaluation or additional testing to support a diagnosis.

COVID in Kids and Fossil-fuel Limits - the Week in Infographics

COVID in Kids and Fossil-fuel Limits - the Week in Infographics

Nature highlights three key infographics from the week in science and research.

Scientists Need to Better Communicate the Links Between Pandemics and Global Environmental Change

Scientists Need to Better Communicate the Links Between Pandemics and Global Environmental Change

The pandemic and global environmental change are intimately intertwined at multiple levels, and this must be more clearly articulated to the public and in policy.

The World's Scientific Panel on Biodiversity Needs a Bigger Role

The World's Scientific Panel on Biodiversity Needs a Bigger Role

IPBES, the international panel of leading biodiversity researchers, should be consulted on how best to measure species loss.

Afghanistan's Terrified Scientists Predict Huge Research Losses

Afghanistan's Terrified Scientists Predict Huge Research Losses

For 20 years, science has blossomed in Afghanistan. Now many researchers are fleeing and those who remain face lost funding and the threat of persecution.

Five Hundred Days Between Pay Cheques: the Road I Took to Revive My Career

Five Hundred Days Between Pay Cheques: the Road I Took to Revive My Career

A global career move left one member of a scientist couple unemployed during the pandemic. Here's what he learnt.

Three Questions to Address Rigour and Reproducibility Concerns in Your Grant Proposal

Three Questions to Address Rigour and Reproducibility Concerns in Your Grant Proposal

Addressing weaknesses and limitations in your science will reassure potential funders, say grant-writing coaches.

Delta's Rise is Fuelled by Rampant Spread from People Who Feel Fine

Delta's Rise is Fuelled by Rampant Spread from People Who Feel Fine

People infected with the Delta variant generally do not have COVID-19 symptoms until two days after they start shedding the coronavirus.

How Do Vaccinated People Spread Delta? What the Science Says

How Do Vaccinated People Spread Delta? What the Science Says

Emerging data suggest that Delta could spread more readily than other coronavirus variants among people vaccinated against COVID-19. But key questions remain.